Roscoe Village is best on a weekday morning before 10am when the day-tripper traffic hasn't arrived and the historic district has a quietness that lets the place actually work on you - the canal basin in that light, the old warehouse buildings, the towpath going north along the water, none of it is performing for anyone at that hour and the difference from a busy Saturday afternoon is significant enough to justify building your first morning around it deliberately rather than just wandering over whenever.
The Warehouse Steak 'n' Stein in Roscoe Village is the kind of regional Ohio restaurant that travel media doesn't write about and locals don't need written about because it's been there and has been the right answer for a specific kind of evening for long enough that it doesn't require external validation - ask staff at the motel about current hours and whether a reservation makes sense for the night you're planning, because weekend evenings in a small town can fill up a good restaurant faster than the size of the town suggests.
Holmes County Amish country to the north rewards a full day rather than a half day if you haven't been before - Berlin and Millersburg as the main towns, the rural roads between them as the actual experience, and the patience to pull over and watch a field being worked with horses rather than driving past it at speed. The food at the Amish restaurants in the area is a specific category of midwestern cooking that deserves more attention than it gets from people who don't already know about it, and arriving hungry is the correct strategy.
Fishing the Muskingum is worth enquiring about with staff when you arrive because local knowledge about current conditions, access points and what's running is worth more than anything on a fishing forum - the river changes with the season and recent weather and the people in this town know it the way people who live next to water always do. A licence is required and available at local hardware and sporting goods stores, and the staff can point you to the right place for that too.
Pack for Ohio weather variability regardless of what the forecast says when you leave home - the Muskingum valley in spring can be genuinely cold in the morning and warm by afternoon and cold again by evening, fall is similar, and the river adds a dampness to the air that makes temperatures feel different from what the number suggests. A layer you don't need is an inconvenience, a layer you need and don't have is a problem, and the second situation is worse than the first by enough to make the decision easy.